Het-PDB Navi2 (PDB: 4UA9)

The number of atoms exceeds 100,000.
So, it can not be displayed here.

Select unit:

Select hetatm:

information

centroid:

interaction residue:

Select chain: Sequence Hide other chain(s)

Data format:

Color scheme of protein:

Ligands
Code	Name		Style	Show	Link
CB4	Pinacol[[2-amino-alpha-(1-carboxy-1-methylethoxyimino)-4-thiazoleacetyl]amino]methaneboronate				PoSSuM
PO4	Phosphate ion				PoSSuM

Non-standard Residues
Code	Name	Show
PCA	Pyroglutamic acid

Glycosylation
Code	Name	Emphasize

Modification
Code	Name	Show

Download interaction data: 4UA9

Code :

4UA9 PDBj RCSB PDB PDBe

Header :

HYDROLASE

Title :

CTX-M-14 Class A Beta-Lactamase in Complex with a Boronic Acid Acylation Transition State Analog at Sub-Angstrom Resolution

Release Data :

2015-06-24

Compound :

mol_id	molecule	chains
1	Beta-lactamase CTX-M-14	A,B

Source :

mol_id	organism_scientific	expression_system
1	Escherichia coli (taxid:562)	Escherichia coli (taxid:469008)
	gene: CTX-M-14 expression_system_strain: BL21(DE3) expression_system_vector_type: plasmid expression_system_plasmid: PET-9a

Authors :

Nichols, D.A., Chen, Y.

Keywords :

CTX-M-14, Class A Beta-Lactamase, Boronic Acid, Acylation Transition State, HYDROLASE

Exp. method :

X-RAY DIFFRACTION ( 0.84 Å )

Citation :

Ligand-Induced Proton Transfer and Low-Barrier Hydrogen Bond Revealed by X-ray Crystallography.

Nichols, D.A.,Hargis, J.C.,Sanishvili, R. et al.
(2015) J.Am.Chem.Soc. 137 : 8086 - 8095

Chain :

A, B

UniProt :

H6UQI0 (H6UQI0_ECOLX)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
a beta-lactam + H2O = a substituted beta-amino acid	3.5.2.6	ARBA:ARBA00001526, RuleBase:RU361140
a beta-lactam + H2O = a substituted beta-amino acid	-	ARBA:ARBA00001526, RuleBase:RU361140

PDB ID: 4UA9