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Ligands
Code Name Style Show Link
GLC Alpha-D-glucopyranose
TW7 2-deoxy-2,2-difluoro-alpha-D-arabino-hexopyranosyl fluoride
: Polysaccharide
Non-standard Residues
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Glycosylation
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Code : 4U2Z   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : X-ray crystal structure of an Sco GlgEI-V279S/1,2,2-trifluromaltose complex
Release Data : 2015-07-22
Compound :
mol_id molecule chains synonym
1 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase 1 A,B GMPMT 1,(1->4)-alpha-D-glucan:maltose-1-phosphate alpha-D-maltosyltransferase 1
ec: 2.4.99.16
mutation: V279S
Source :
mol_id organism_scientific expression_system
1 Streptomyces coelicolor  (taxid:100226) Escherichia coli  (taxid:562)
strain: ATCC BAA-471 / A3(2) / M145
gene: glgE1, pep1, pep1A, pep1I, SCO5443, SC6A11.19c
Authors : Ronning, D.R., Lindenberger, J.J.
Keywords : Inhibitor Complex Fluorosugar Maltosyl Transferase, Transferase
Exp. method : X-RAY DIFFRACTION ( 2.26 Å )
Citation :

Synthesis of 2-deoxy-2,2-difluoro-alpha-maltosyl fluoride and its X-ray structure in complex with Streptomyces coelicolor GlgEI-V279S.

Thanna, S.,Lindenberger, J.J.,Gaitonde, V.V.  et al.
(2015)  Org.Biomol.Chem.  13 : 7542 - 7550

PubMed: 26072729
DOI: 10.1039/c5ob00867k

Chain : A, B
UniProt : Q9L1K2 (GLGE1_STRCO)
Reaction: EC: Evidence:
Physiological Direction:
[(1->4)-alpha-D-glucosyl](n) + alpha-maltose 1-phosphate = [(1->4)-alpha-D-glucosyl](n+2) + phosphate 2.4.99.16 PubMed:21914799
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