PDB ID: 4TU5
Hetero Atom Contents
The number of atoms exceeds 100,000. So, it can not be displayed here.
Select unit:
Select hetatm:
Select chain: Sequence
Data format:
Color scheme of protein:
Code | Name | Style | Show | Link | |
---|---|---|---|---|---|
06W | 6-ethyl-5-{(3s)-3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl}pyrimidine-2,4-diamine | PoSSuM | |||
NDP | Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate | PoSSuM |
Code | Name | Show |
---|
Code | Name | Emphasize |
---|
Code | Name | Show |
---|
Download interaction data: 4TU5
Structure summary
Code : | 4TU5 PDBj RCSB PDB PDBe | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Header : | OXIDOREDUCTASE/OXIDOREDUCTASE Inhibitor | ||||||||||||
Title : | Staphylococcus aureus Dihydrofolate Reductase complexed with NADPH and 6-ETHYL-5-[(3S)-3-[3-METHOXY-5-(PYRIDIN-4-YL)PHENYL]BUT-1-YN-1-YL]PYRIMIDINE-2,4-DIAMINE (UCP1062) | ||||||||||||
Release Data : | 2015-07-08 | ||||||||||||
Compound : |
|
||||||||||||
Source : |
|
||||||||||||
Authors : | Reeve, S.M., Anderson, A.C. | ||||||||||||
Keywords : | Dihydrofolate reductase, Oxidoreductase, Methicillin-resistant Staphylococcus aureus, Antifolates, Enantiopure Inhibitors, OXIDOREDUCTASE-OXIDOREDUCTASE Inhibitor complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.161 Å ) | ||||||||||||
Citation : |
Nonracemic Antifolates Stereoselectively Recruit Alternate Cofactors and Overcome Resistance in S. aureus.
Keshipeddy, S.,Reeve, S.M.,Anderson, A.C.
et al.
PubMed: 26098608 |
Reaction
Chain : | X |
---|---|
UniProt : | Q2YY41 |
Reaction : | - |