Brand  (β version)

PDB ID: 4RLH

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Ligands
Code Name Style Show Link
0WE N-methyl-N-[(3-methyl-1-benzofuran-2-yl)methyl]-3-(7-oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-3-yl)propanamide PoSSuM
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Structure summary

Code : 4RLH   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : Crystal structure of enoyl ACP reductase from Burkholderia pseudomallei in complex with AFN-1252
Release Data : 2015-12-09
Compound :
mol_id molecule chains
1 Enoyl-[acyl-carrier-protein] reductase [NADH] A,B,D,C
ec: 1.3.1.9
Source :
mol_id organism_scientific expression_system
1 Burkholderia pseudomallei  (taxid:272560) Escherichia coli  (taxid:469008)
strain: K96243
gene: fabI, BPSL2204
expression_system_strain: Bl21(DE3)star
expression_system_vector_type: plasmid
expression_system_plasmid: pET21a
Authors : Rao, K.N., Sarah, J., Anirudha, L., Subramanya, H.S.
Keywords : Rossmann Fold, enoyl ACP reductase, FabI, AFN-1252, OXIDOREDUCTASE
Exp. method : X-RAY DIFFRACTION ( 2.26 Å )
Citation :

Crystal structure of enoyl ACP reductase from Burkholderia pseudomallei in complex with AFN-1252

Rao, N.K.,Sarah, J.,Anirudha, L.  et al.
To be Published 

Reaction

Chain : A, B, D, C
UniProt : Q63SW7 (Q63SW7_BURPS)
Reaction: EC: Evidence:
Physiological Direction:
a 2,3-saturated acyl-[ACP] + NAD(+) = a (2E)-enoyl-[ACP] + H(+) + NADH 1.3.1.9 PIRNR:PIRNR000094
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