Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
0TT 1-[(2r,4s,5r)-5-(hydroxymethyl)-4-oxidanyl-oxolan-2-yl]-5-[[(5r)-1-[(2r,4s,5r)-5-(hydroxymethyl)-4-oxidanyl-oxolan-2-yl]-5-methyl-2,4-bis(oxidanylidene)-1,3-diazinan-5-yl]methyl]pyrimidine-2,4-dione
EEM [(3s)-3-amino-4-hydroxy-4-oxo-butyl]-[[(2s,3s,4r,5r)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl]-methyl-selanium
SF4 Iron/sulfur cluster
SO4 Sulfate ion
Code : 4RH1   PDBj   RCSB PDB   PDBe
Header : LYASE
Title : Spore photoproduct lyase C140A/S76C mutant with bound AdoMet and dinucleoside spore photoproduct
Release Data : 2014-10-22
Compound :
mol_id molecule chains
1 Spore photoproduct lyase A
ec: 4.1.99.14
mutation: C140A, S76C
Source :
mol_id organism_scientific expression_system
1 Geobacillus thermodenitrificans NG80-2  (taxid:420246) Escherichia coli  (taxid:562)
gene: GTNG_2348
Authors : Benjdia, A., Heil, K., Winkler, A., Carell, T., Schlichting, I.
Keywords : radical AdoMet enzyme, radical SAM enzyme, DNA repair, Tim Barrel, DNA lyase, LYASE
Exp. method : X-RAY DIFFRACTION ( 2.60 Å )
Citation :

Rescuing DNA repair activity by rewiring the H-atom transfer pathway in the radical SAM enzyme, spore photoproduct lyase.

Benjdia, A.,Heil, K.,Winkler, A.  et al.
(2014)  Chem.Commun.(Camb.)  50 : 14201 - 14204

PubMed: 25285338
DOI: 10.1039/c4cc05158k

Chain : A
UniProt : A4IQU1 (No found in current UniProtKB/SwissProt)
Reaction : -