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Ligands
Code Name Style Show Link
C6N 6-cyclohexyl-2-(4-cyclohexylbutyl)-2-({[4-O-(alpha-D-glucopyranosyl)-beta-D-glucopyranosyl]oxy}methyl)hexyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside
CA Calcium ion
CL Chloride ion
GOL Glycerol
K Potassium ion
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Code : 4RDQ   PDBj   RCSB PDB   PDBe
Header : TRANSPORT PROTEIN
Title : Calcium-activated chloride channel bestrophin-1, from chicken, in complex with Fab antibody fragments, chloride and calcium
Release Data : 2014-10-22
Compound :
mol_id molecule chains synonym
1 Bestrophin-1 A,B,C,D,E Best1
fragment: UNP residues 2-405
mol_id molecule chains
2 Fab antibody fragment, light chain F,H,J,L,N
mol_id molecule chains
3 Fab antibody fragment, heavy chain G,I,K,M,O
Source :
mol_id organism_scientific organism_common expression_system
1 Gallus gallus  (taxid:9031) Bantam,chickens Pichia pastoris  (taxid:4922)
gene: Best1 bestrophin-1
mol_id organism_scientific organism_common
2 Mus musculus  (taxid:10090) Mouse
other_details: antibody secreted from hybridoma cells
mol_id organism_scientific organism_common
3 Mus musculus  (taxid:10090) Mouse
other_details: antibody secreted from hybridoma cells
Authors : Dickson, V.K., Pedi, L., Long, S.B.
Keywords : transmembrane protein, membrane protein, ion channel, calcium-activated chloride channel, CaCC, anion channel, membrane, TRANSPORT PROTEIN
Exp. method : X-RAY DIFFRACTION ( 2.850 Å )
Citation :

Structure and insights into the function of a Ca(2+)-activated Cl(-) channel.

Kane Dickson, V.,Pedi, L.,Long, S.B.
(2014)  Nature  516 : 213 - 218

PubMed: 25337878
DOI: 10.1038/nature13913

Chain : A, B, C, D, E
UniProt : E1C3A0
Reaction : -