Brand  (β version)

color scheme of protein:

hetatm:

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information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
CA Calcium ion
0XR Ethyl (2e)-3-(3,4-dihydroxyphenyl)prop-2-enoate
Code : 4PWG
Header : TRANSPORT PROTEIN
Title : Crystal structure of V30M mutant human transthyretin complexed with caffeic acid ethyl ester
Release Data : 2014-11-26
Compound :
mol_id molecule chains synonym
1 Transthyretin A,B ATTR, Prealbumin, TBPA
mutation: V30M
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: TTR
expression_system_strain: M30
expression_system_vector_type: PLASMID
expression_system_plasmid: pQE-30
Authors : Yokoyama, T., Kosaka, Y., Mizuguchi, M.
Keywords : Tranporter, thyroxine binding, TRANSPORT PROTEIN
Exp. method : X-RAY DIFFRACTION ( 1.798 Å )
Citation :

Inhibitory Activities of Propolis and Its Promising Component, Caffeic Acid Phenethyl Ester, against Amyloidogenesis of Human Transthyretin

Yokoyama, T.,Kosaka, Y.,Mizuguchi, M.
(2014)  J.Med.Chem.  57 : 8928 - 8935

PubMed: 25314129
DOI: 10.1021/jm500997m

Chain : A, B
UniProt : P02766 (TTHY_HUMAN)
Reaction : -