Het-PDB Navi2 (PDB: 4PWG)

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Ligands
Code	Name		Style	Show	Link
0XR	Ethyl (2e)-3-(3,4-dihydroxyphenyl)prop-2-enoate				PoSSuM
CA	Calcium ion				PoSSuM

Non-standard Residues
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Download interaction data: 4PWG

Code :

4PWG PDBj RCSB PDB PDBe

Header :

TRANSPORT PROTEIN

Title :

Crystal structure of V30M mutant human transthyretin complexed with caffeic acid ethyl ester

Release Data :

2014-11-26

Compound :

mol_id	molecule	chains	synonym
1	Transthyretin	A,B	ATTR, Prealbumin, TBPA
	mutation: V30M

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	gene: TTR expression_system_strain: M30 expression_system_vector_type: PLASMID expression_system_plasmid: pQE-30

Authors :

Yokoyama, T., Kosaka, Y., Mizuguchi, M.

Keywords :

Tranporter, thyroxine binding, TRANSPORT PROTEIN

Exp. method :

X-RAY DIFFRACTION ( 1.798 Å )

Citation :

Inhibitory Activities of Propolis and Its Promising Component, Caffeic Acid Phenethyl Ester, against Amyloidogenesis of Human Transthyretin

Yokoyama, T.,Kosaka, Y.,Mizuguchi, M.
(2014) J.Med.Chem. 57 : 8928 - 8935

PDB ID: 4PWG