PDB ID: 4PV0
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Structure summary
Code : | 4PV0 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE/TRANSFERASE INHIBITOR | ||||||||||||
Title : | Crystal structure of spleen tyrosine kinase (Syk) in complex with an imidazopyrazine inhibitor | ||||||||||||
Release Data : | 2014-05-21 | ||||||||||||
Compound : |
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Source : |
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Authors : | Lansdon, E.B., Mitchell, S.A. | ||||||||||||
Keywords : | Syk, spleen tyrosine kinase, kinase inhibitor, protein kinase, TRANSFERASE-TRANSFERASE INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.000 Å ) | ||||||||||||
Citation : |
Discovery of GS-9973, a Selective and Orally Efficacious Inhibitor of Spleen Tyrosine Kinase.
Currie, K.S.,Kropf, J.E.,Lee, T.
et al.
PubMed: 24779514 |
Reaction
Chain : | A | ||||||||
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UniProt : | P43405 (KSYK_HUMAN) | ||||||||
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