Het-PDB Navi2 (PDB: 4PRG)

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Ligands
Code	Name		Style	Show	Link
072	(+/-)(2s,5s)-3-(4-(4-carboxyphenyl)butyl)-2-heptyl-4-oxo-5-thiazolidine				PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 4PRG

Code :

4PRG PDBj RCSB PDB PDBe

Header :

RECEPTOR

Title :

0072 PARTIAL AGONIST PPAR GAMMA COCRYSTAL

Release Data :

1999-05-27

Compound :

mol_id	molecule	chains
1	PROTEIN (PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA)	A,B,C,D
	fragment: LIGAND BINDING DOMAIN, RESIDUES 207-476 other_details: 0072 PARTIAL AGONIST COCRYSTAL

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:562)
	gene: HPPARGAMMA other_details: PLASMID IS PRSET A

Authors :

Milburn, M.V.

Keywords :

THIAZOLIDINONE, LIGAND-BINDING DOMAIN, NUCLEAR RECEPTOR, ORPHAN RECEPTOR, RECEPTOR

Exp. method :

X-RAY DIFFRACTION ( 2.90 Å )

Citation :

A peroxisome proliferator-activated receptor gamma ligand inhibits adipocyte differentiation.

Oberfield, J.L.,Collins, J.L.,Holmes, C.P. et al.
(1999) Proc.Natl.Acad.Sci.USA 96 : 6102 - 6106

Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma.

Nolte, R.T.,Wisely, G.B.,Westin, S. et al.
(1998) Nature 395 : 137 - 143

PDB ID: 4PRG