Het-PDB Navi2 (PDB: 4PME)

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Ligands
Code	Name	Link
CUR	(1z,4z,6e)-5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-one	PoSSuM
NA	Sodium ion	PoSSuM
EDO	1,2-ethanediol	PoSSuM
FER	3-(4-hydroxy-3-methoxyphenyl)-2-propenoic acid	PoSSuM

Non-standard Residues
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Glycosylation
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Download interaction data: 4PME

Code :

4PME PDBj RCSB PDB PDBe

Header :

Thyroid hormone-binding protein

Title :

Human transthyretin (TTR) complexed with ferulic acid and curcumin.

Release Data :

2014-10-08

Compound :

mol_id	molecule	chains	synonym
1	Transthyretin	A,B	ATTR,Prealbumin,TBPA
	fragment: UNP residues 29-145

Source :

mol_id	organism_scientific	organism_common
1	Homo sapiens (taxid:9606)	Human

Authors :

Stura, E.A., Ciccone, L.

Keywords :

Human transthyretin (TTR) complexes, solubilization of hydrophobic ligands, curcumin degradation, Thyroid hormone-binding protein

Exp. method :

X-RAY DIFFRACTION ( 1.264 Å )

Citation :

Transthyretin complexes with curcumin and bromo-estradiol: evaluation of solubilizing multicomponent mixtures.

Ciccone, L.,Tepshi, L.,Nencetti, S. et al.
(2014) N Biotechnol 32 : 54 - 64

PDB ID: 4PME