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Ligands
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CE3 (6r,7r)-3-(acetyloxymethyl)-7-[[(2z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-ethanoyl]amino]-8-oxo-5-thia-1-azabicy clo[4.2.0]oct-2-ene-2-carboxylic acid
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Code : 4PM9   PDBj   RCSB PDB   PDBe
Header : HYDROLASE/ANTIBIOTIC
Title : Crystal structure of CTX-M-14 S70G:S237A:R276A beta-lactamase in complex with cefotaxime at 1.45 Angstroms resolution
Release Data : 2014-12-31
Compound :
mol_id molecule chains
1 Beta-lactamase CTX-M-14 A
fragment: UNP residues 29-291
Source :
mol_id organism_scientific expression_system
1 Klebsiella pneumoniae subsp. pneumoniae  (taxid:1125630) Escherichia coli  (taxid:562)
strain: HS11286
gene: KPHS_p301310
Authors : Cardenas, A.M., Adamski, C.J., Sankaran, B., Brown, N.G., Horton, L.B., Palzkill, T.
Keywords : Class A beta-lactamase, cefotaxime, HYDROLASE-ANTIBIOTIC complex
Exp. method : X-RAY DIFFRACTION ( 1.454 Å )
Citation :

Molecular Basis for the Catalytic Specificity of the CTX-M Extended-Spectrum beta-Lactamases.

Adamski, C.J.,Cardenas, A.M.,Brown, N.G.  et al.
(2015)  Biochemistry  54 : 447 - 457

PubMed: 25489790
DOI: 10.1021/bi501195g

Chain : A
UniProt : G8XD06
Reaction : -