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Ligands
Code Name Style Show Link
GLU Glutamic acid
GLY Glycine
QEL 4-[(1r,2s)-2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl]phenol
W Tungsten ion
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
BMA Beta-D-mannopyranose
MAN Alpha-D-mannopyranose
NAG 2-acetamido-2-deoxy-beta-D-glucopyranose
Modification
Code Name Show
Code : 4PE5   PDBj   RCSB PDB   PDBe
Header : TRANSPORT PROTEIN
Title : Crystal Structure of GluN1a/GluN2B NMDA Receptor Ion Channel
Release Data : 2014-06-04
Compound :
mol_id molecule chains synonym
1 Glutamate receptor ionotropic, NMDA 1 A,C GluN1,Glutamate [NMDA] receptor subunit zeta-1,N-methyl-D-aspartate receptor subunit NR1,NMD-R1
fragment: UNP residues 23-847
mutation: N61Q, N239D, N350Q, N471Q, N491Q, T561C, E594Q, E595S, E597S, E598T, N771Q, F810C, R844N, R845G, K846A
mol_id molecule chains synonym
2 Glutamate receptor ionotropic, NMDA 2B B,D GluN2B,Glutamate [NMDA] receptor subunit epsilon-2,N-methyl D-aspartate receptor subtype 2B,NR2B
fragment: UNP residues 27-852
mutation: S214C, N348D, D557C, C588S, I815C, C838S, C849S, del(C395), del(P396), del(E397), del(E399), del(E400), del(E402)
Source :
mol_id organism_scientific organism_common expression_system
1 Rattus norvegicus  (taxid:10116) Rat Spodoptera frugiperda  (taxid:7108)
gene: Grin1, Nmdar1
mol_id organism_scientific organism_common expression_system
2 Rattus norvegicus  (taxid:10116) Rat Spodoptera frugiperda  (taxid:7108)
gene: Grin2b
Authors : Karakas, E., Furukawa, H.
Keywords : NMDA receptor, GluN1, GluN2B, ion channel, TRANSPORT PROTEIN
Exp. method : X-RAY DIFFRACTION ( 3.96 Å )
Citation :

Crystal structure of a heterotetrameric NMDA receptor ion channel.

Karakas, E.,Furukawa, H.
(2014)  Science  344 : 992 - 997

PubMed: 24876489
DOI: 10.1126/science.1251915

Chain : A, C
UniProt : P35439 (NMDZ1_RAT)
Reaction : -
Chain : B, D
UniProt : Q00960 (NMDE2_RAT)
Reaction : -