Het-PDB Navi2 (PDB: 4OCA)

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Ligands
Code	Name		Style	Show	Link
2QR	(2r,3r,4s,5s)-3,4-dihydroxy-5-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]tetrahydro-2h-pyr an-2-yl [(2r,3s,4r,5r)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate				PoSSuM

Non-standard Residues
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Download interaction data: 4OCA

Code :

4OCA PDBj RCSB PDB PDBe

Header :

TRANSFERASE

Title :

Cryatal structure of ArnB K188A complexted with PLP and UDP-Ara4N

Release Data :

2014-03-12

Compound :

mol_id	molecule	chains	synonym
1	UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase	A	UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase, UDP-4-amino-4-deoxy-L-arabinose aminotransferase
	ec: 2.6.1.87 mutation: K188A

Source :

mol_id	organism_scientific	expression_system
1	Salmonella enterica subsp. enterica serovar Typhimurium (taxid:90371)	Escherichia coli (taxid:562)
	gene: yfbE, arnB

Authors :

Sousa, M.C., Lee, M.

Keywords :

Aminotransferase, TRANSFERASE

Exp. method :

X-RAY DIFFRACTION ( 2.300 Å )

Citation :

Structural Basis for Substrate Specificity in ArnB. A Key Enzyme in the Polymyxin Resistance Pathway of Gram-Negative Bacteria.

Lee, M.,Sousa, M.C.
(2014) Biochemistry 53 : 796 - 805

PDB ID: 4OCA