Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
2QR (2r,3r,4s,5s)-3,4-dihydroxy-5-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)amino]tetrahydro-2h-pyran-2-yl [(2r,3s,4r,5r)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2h)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate
Code : 4OCA
Header : TRANSFERASE
Title : Cryatal structure of ArnB K188A complexted with PLP and UDP-Ara4N
Release Data : 2014-03-12
Compound :
mol_id molecule chains synonym
1 UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase A UDP-(beta-L-threo-pentapyranosyl-4''-ulose diphosphate) aminotransferase, UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ec: 2.6.1.87
mutation: K188A
Source :
mol_id organism_scientific expression_system
1 Salmonella enterica subsp. enterica serovar Typhimurium  (taxid:90371) Escherichia coli  (taxid:562)
gene: yfbE, arnB
Authors : Sousa, M.C., Lee, M.
Keywords : Aminotransferase, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 2.300 Å )
Citation :

Structural Basis for Substrate Specificity in ArnB. A Key Enzyme in the Polymyxin Resistance Pathway of Gram-Negative Bacteria.

Lee, M.,Sousa, M.C.
(2014)  Biochemistry  53 : 796 - 805

PubMed: 24460375
DOI: 10.1021/bi4015677

Chain : A
UniProt : F5ZUF5 (No found in current UniProtKB/SwissProt)
Reaction : -