PDB ID: 4O5E
Hetero Atom Contents
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Data format:
Color scheme of protein:
Code | Name | Style | Show | Link | |
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1FZ | 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine | PoSSuM | |||
MG | Magnesium ion | PoSSuM | |||
NA | Sodium ion | PoSSuM |
Code | Name | Show |
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FMG | 2-amino-9-(2-deoxy-2-fluoro-5-O-phosphono-beta-D-arabinofuranosyl)-7-methyl-6-oxo-6,9-dihydro-1h-purin-7-ium |
Code | Name | Emphasize |
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Code | Name | Show |
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Download interaction data: 4O5E
Structure summary
Code : | 4O5E PDBj RCSB PDB PDBe | ||||||||||||||||||||||||||||||||||||||||||||||||
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Header : | Transferase, Lyase/DNA | ||||||||||||||||||||||||||||||||||||||||||||||||
Title : | Structure of human DNA polymerase complexed with N7MG in the template base paired with incoming non-hydrolyzable TTP | ||||||||||||||||||||||||||||||||||||||||||||||||
Release Data : | 2014-07-02 | ||||||||||||||||||||||||||||||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Koag, M.C., Lee, S. | ||||||||||||||||||||||||||||||||||||||||||||||||
Keywords : | DNA binding, polymerase fold, nucleotidyl transfer, DNA, nucleus, Transferase, Lyase-DNA complex | ||||||||||||||||||||||||||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.5320 Å ) | ||||||||||||||||||||||||||||||||||||||||||||||||
Citation : |
Transition-state destabilization reveals how human DNA polymerase beta proceeds across the chemically unstable lesion N7-methylguanine.
Koag, M.C.,Kou, Y.,Ouzon-Shubeita, H.
et al.
PubMed: 24966350 |
Reaction
Chain : | A | ||||||||||||||||
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UniProt : | P06746 (DPOLB_HUMAN) | ||||||||||||||||
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