PDB ID: 4NY8
Hetero Atom Contents
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Data format:
Color scheme of protein:
Code | Name | Style | Show | Link | |
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0KX | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine | PoSSuM | |||
MN | Manganese (II) ion | PoSSuM | |||
NA | Sodium ion | PoSSuM |
Code | Name | Show |
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6OG | 6-O-methyl guanosine-5'-monophosphate |
Code | Name | Emphasize |
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Code | Name | Show |
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Download interaction data: 4NY8
Structure summary
Code : | 4NY8 PDBj RCSB PDB PDBe | ||||||||||||||||||||||||||||||||||||||||||||||||
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Header : | TRANSFERASE, LYASE/DNA | ||||||||||||||||||||||||||||||||||||||||||||||||
Title : | DNA polymerase beta with O6mG in the template base opposite to incoming non-hydrolyzable CTP with manganese in the active site | ||||||||||||||||||||||||||||||||||||||||||||||||
Release Data : | 2014-04-16 | ||||||||||||||||||||||||||||||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Koag, M.-C., Min, K., Monzingo, A.F., Lee, S. | ||||||||||||||||||||||||||||||||||||||||||||||||
Keywords : | DNA binding, DNA polymerase fold, nucleotidyl transfer, nucleolus, TRANSFERASE, LYASE-DNA complex | ||||||||||||||||||||||||||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.246 Å ) | ||||||||||||||||||||||||||||||||||||||||||||||||
Citation : |
Metal-dependent conformational activation explains highly promutagenic replication across O6-methylguanine by human DNA polymerase beta.
Koag, M.C.,Lee, S.
PubMed: 24694247 |
Reaction
Chain : | A | ||||||||||||||||
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UniProt : | P06746 (DPOLB_HUMAN) | ||||||||||||||||
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