PDB ID: 4NPV
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Structure summary
Code : | 4NPV PDBj RCSB PDB PDBe | ||||||||||||
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Header : | HYDROLASE/HYDROLASE INHIBITOR | ||||||||||||
Title : | Crystal structure of human PDE1B bound to inhibitor 7A (6,7,8-trimethoxy-N-(pentan-3-yl)quinazolin-4-amine) | ||||||||||||
Release Data : | 2014-07-16 | ||||||||||||
Compound : |
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Source : |
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Authors : | Pandit, J., Evdomikov, A., Mansour, M., Simons, S. | ||||||||||||
Keywords : | HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.40 Å ) | ||||||||||||
Citation : |
Small-molecule phosphodiesterase probes: discovery of potent and selective CNS-penetrable quinazoline inhibitors of PDE1
Humphrey, J.M.,Yang, E.X.,Am Ende, C.W.
et al.
DOI: 10.1039/C4MD00113C |
Reaction
Chain : | A | |||||||||||||||||||
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UniProt : | Q01064 (PDE1B_HUMAN) | |||||||||||||||||||
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