Het-PDB Navi2 (PDB: 4NMT)

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Ligands
Code	Name		Style	Show	Link
GOL	Glycerol				PoSSuM

Non-standard Residues
Code	Name	Show
FAK	N~6~-(trifluoroacetyl)-L-lysine

Glycosylation
Code	Name	Emphasize

Modification
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Download interaction data: 4NMT

Code :

4NMT PDBj RCSB PDB PDBe

Header :

protein transport/inhibitor

Title :

CFTR Associated Ligand (CAL) PDZ domain bound to peptide iCAL36(TFA-K-1) (ANSRWPTS[Tfa-acyl-K]I)

Release Data :

2014-10-01

Compound :

mol_id	molecule	chains	synonym
1	Golgi-associated PDZ and coiled-coil motif-containing protein	A,B	CFTR-associated ligand, Fused in glioblastoma, PDZ protein interacting specifically with TC10, PIST
	fragment: UNP RESIDUES 284-370

mol_id	molecule	chains
2	iCAL36(TFA-K-1) peptide	C,D

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:469008)
	gene: GOPC, CAL, FIG expression_system_strain: BL21(DE3)RIL expression_system_vector_type: plasmid expression_system_plasmid: pET16b

mol_id	organism_scientific
2
	synthetic: yes

Authors :

Amacher, J.F., Madden, D.R.

Keywords :

CAL, PIST, GOPC, FIG, CFTR, PDZ, PDZ-peptide, protein transport-inhibitor complex

Exp. method :

X-RAY DIFFRACTION ( 1.4 Å )

Citation :

Chemically Modified Peptide Scaffolds Target the CFTR-Associated Ligand PDZ Domain.

Amacher, J.F.,Zhao, R.,Spaller, M.R. et al.
(2014) Plos One 9 : e103650 - e103650

PDB ID: 4NMT