Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
2JX 5-[(2r)-2,3-dihydro-1,4-benzodioxin-2-yl]-2,4-dihydro-3h-1,2,4-triazole-3-thione
CMO Carbon monoxide
HEM Protoporphyrin ix containing Fe
MBN Toluene
Code : 4NI1
Header : OXYGEN TRANSPORT
Title : Qauternary R CO-liganded hemoglobin structure in complex with a thiol containing compound
Release Data : 2014-09-17
Compound :
mol_id molecule chains synonym
1 Hemoglobin subunit alpha A Alpha-globin, Hemoglobin alpha chain
mol_id molecule chains synonym
2 Hemoglobin subunit beta B Beta-globin, Hemoglobin beta chain
Source :
mol_id organism_scientific organism_common
1 Homo sapiens  (taxid:9606) Human
mol_id organism_scientific organism_common
2 Homo sapiens  (taxid:9606) Human
Authors : Safo, M.K., Meadows, J., Ko, T.-P., Nakagawa, A., Zapol, W.
Keywords : allosteric, tetramer, oxygen transport, relaxed state, tense state, globin fold, Red blood cell
Exp. method : X-RAY DIFFRACTION ( 1.90 Å )
Citation :

Identification of a Small Molecule that Increases Hemoglobin Oxygen Affinity and Reduces SS Erythrocyte Sickling.

Nakagawa, A.,Lui, F.E.,Wassaf, D.  et al.
(2014)  Acs Chem.Biol.  9 : 2318 - 2325

PubMed: 25061917
DOI: 10.1021/cb500230b

Chain : A
UniProt : P69905 (HBA_HUMAN)
Reaction : -
Chain : B
UniProt : P68871 (HBB_HUMAN)
Reaction : -