PDB ID: 4NFJ
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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JD5 | [({5-[4-(cyclopropyloxy)phenyl]pyridin-3-yl}amino)methanediyl]bis(phosphonic acid) | PoSSuM | |||
MG | Magnesium ion | PoSSuM | |||
SO4 | Sulfate ion | PoSSuM |
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Download interaction data: 4NFJ
Structure summary
Code : | 4NFJ PDBj RCSB PDB PDBe | ||||||||||||
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Header : | Transferase/Transferase inhibitor | ||||||||||||
Title : | Crystal structure of human FPPS in complex with magnesium, JDS05120, and sulfate | ||||||||||||
Release Data : | 2014-12-31 | ||||||||||||
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Authors : | Park, J., De Schutter, J.W., Tsantrizos, Y.S., Berghuis, A.M. | ||||||||||||
Keywords : | Transferase-Transferase inhibitor complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.05 Å ) | ||||||||||||
Citation : |
Crystallographic and thermodynamic characterization of phenylaminopyridine bisphosphonates binding to human farnesyl pyrophosphate synthase.
Park, J.,Rodionov, D.,De Schutter, J.W.
et al.
PubMed: 29036218 |
Reaction
Chain : | F | ||||||||||||
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UniProt : | P14324 (FPPS_HUMAN) | ||||||||||||
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