Het-PDB Navi2 (PDB: 4MQW)

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Ligands
Code	Name		Style	Show	Link
EDO	1,2-ethanediol				PoSSuM

Non-standard Residues
Code	Name	Show
TYS	O-sulfo-L-tyrosine

Glycosylation
Code	Name	Emphasize
NAG	2-acetamido-2-deoxy-beta-D-glucopyranose

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Download interaction data: 4MQW

Code :

4MQW PDBj RCSB PDB PDBe

Header :

SIGNALING PROTEIN

Title :

Structure of follicle-stimulating hormone in complex with the entire ectodomain of its receptor (P31)

Release Data :

2014-04-09

Compound :

mol_id	molecule	chains
1	Glycoprotein hormones, alpha polypeptide	A,D,G

mol_id	molecule	chains	synonym
2	Follitropin subunit beta	B,E,H	Follicle-stimulating hormone beta subunit, FSH-B, FSH-beta, Follitropin beta chain

mol_id	molecule	chains	synonym
3	Follicle-stimulating hormone receptor	X,Y,Z	FSH-R, Follitropin receptor
	mutation: C188S

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Homo sapiens (taxid:9606)
	gene: CGA expression_system_cell_line: HEK293 expression_system_vector_type: PLASMID expression_system_plasmid: PVLAD6

mol_id	organism_scientific	organism_common	expression_system
2	Homo sapiens (taxid:9606)	Human	Homo sapiens (taxid:9606)
	gene: FSHB expression_system_cell_line: HEK293 expression_system_vector_type: PLASMID expression_system_plasmid: PVLAD6

mol_id	organism_scientific	organism_common	expression_system
3	Homo sapiens (taxid:9606)	Human	Homo sapiens (taxid:9606)
	gene: FSHR, LGR1 expression_system_cell_line: HEK293 expression_system_vector_type: PLASMID expression_system_plasmid: PVLAD6

Authors :

Jiang, X., Liu, H., Chen, X., He, X.

Keywords :

cystine-knot, leucine-rich repeats, Glycoprotein hormone, GPCR, Sulfation, SIGNALING PROTEIN

Exp. method :

X-RAY DIFFRACTION ( 2.90 Å )

Citation :

Evidence for Follicle-stimulating Hormone Receptor as a Functional Trimer.

Jiang, X.,Fischer, D.,Chen, X. et al.
(2014) J.Biol.Chem. 289 : 14273 - 14282

PDB ID: 4MQW