Het-PDB Navi2 (PDB: 4MJR)

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Ligands
Code	Name	Link
0LA	(2s)-2-(6-chloro-9h-carbazol-2-yl)propanoic acid	PoSSuM
CA	Calcium ion	PoSSuM
CL	Chloride ion	PoSSuM
PEG	Di(hydroxyethyl)ether	PoSSuM
PGE	Triethylene glycol	PoSSuM

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Download interaction data: 4MJR

Code :

4MJR PDBj RCSB PDB PDBe

Header :

TRANSFERASE/TRANSFERASE INHIBITOR

Title :

E. coli sliding clamp in complex with (S)-Carprofen

Release Data :

2013-09-18

Compound :

mol_id	molecule	chains	synonym
1	DNA polymerase III subunit beta	A,B	Beta sliding clamp, Beta clamp
	ec: 2.7.7.7

Source :

mol_id	organism_scientific	expression_system
1	Escherichia coli (taxid:83333)	Escherichia coli (taxid:562)
	strain: K12 gene: b3701, dnaN, JW3678 expression_system_vector_type: Plasmid expression_system_plasmid: pND261

Authors :

Yin, Z., Oakley, A.J.

Keywords :

PolIII beta, sliding clamp, DnaN, TRANSFERASE-TRANSFERASE INHIBITOR complex

Exp. method :

X-RAY DIFFRACTION ( 1.62 Å )

Citation :

DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs.

Yin, Z.,Wang, Y.,Whittell, L.R. et al.
(2014) Chem.Biol. 21 : 481 - 487

PDB ID: 4MJR