Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
CA Calcium ion
CL Chloride ion
0LA (2s)-2-(6-chloro-9h-carbazol-2-yl)propanoic acid
PEG Di(hydroxyethyl)ether
PGE Triethylene glycol
Code : 4MJR
Header : TRANSFERASE/TRANSFERASE INHIBITOR
Title : E. coli sliding clamp in complex with (S)-Carprofen
Release Data : 2013-09-18
Compound :
mol_id molecule chains synonym
1 DNA polymerase III subunit beta A,B Beta sliding clamp, Beta clamp
ec: 2.7.7.7
Source :
mol_id organism_scientific expression_system
1 Escherichia coli  (taxid:83333) Escherichia coli  (taxid:562)
strain: K12
gene: b3701, dnaN, JW3678
expression_system_vector_type: Plasmid
expression_system_plasmid: pND261
Authors : Yin, Z., Oakley, A.J.
Keywords : PolIII beta, sliding clamp, DnaN, TRANSFERASE-TRANSFERASE INHIBITOR complex
Exp. method : X-RAY DIFFRACTION ( 1.62 Å )
Citation :

DNA replication is the target for the antibacterial effects of nonsteroidal anti-inflammatory drugs.

Yin, Z.,Wang, Y.,Whittell, L.R.  et al.
(2014)  Chem.Biol.  21 : 481 - 487

PubMed: 24631121
DOI: 10.1016/j.chembiol.2014.02.009

Chain : A, B
UniProt : P0A988 (DPO3B_ECOLI)
Reaction : Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).