PDB ID: 4LVV
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Structure summary
Code : | 4LVV PDBj RCSB PDB PDBe | ||||||||||||
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Header : | RNA | ||||||||||||
Title : | Structure of the THF riboswitch | ||||||||||||
Release Data : | 2014-03-19 | ||||||||||||
Compound : |
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Authors : | Trausch, J.J., Batey, R.T. | ||||||||||||
Keywords : | Aptamers, Nucleotide, Bacterial Proteins, Base Sequence, Binding Sites, Calorimetry, Folic Acid, Gene Expression Regulation, Bacterial, Guanine, Leucovorin, Ligands, Magnesium, Molecular Sequence Data, Nucleic Acid Conformation, Point Mutation, Protein Binding, S-Adenosylmethionine, Streptococcus mutans, Terminator Regions, Genetic, Tetrahydrofolates, Thermodynamics, Transcription, three-way junction, pseudoknot, regulation, ncRNA, THF binding, mRNA, RNA | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.100 Å ) | ||||||||||||
Citation : |
A Disconnect between High-Affinity Binding and Efficient Regulation by Antifolates and Purines in the Tetrahydrofolate Riboswitch.
Trausch, J.J.,Batey, R.T.
PubMed: 24388757 The structure of a tetrahydrofolate-sensing riboswitch reveals two ligand binding sites in a single aptamer.
Trausch, J.J.,Ceres, P.,Reyes, F.E.
et al.
PubMed: 21906956 |