Het-PDB Navi2 (PDB: 4LQ9)

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Ligands
Code	Name		Style	Show	Link
21D	Naphthalene-1,5-disulfonic acid				PoSSuM
MG	Magnesium ion				PoSSuM

Non-standard Residues
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Download interaction data: 4LQ9

Code :

4LQ9 PDBj RCSB PDB PDBe

Header :

VIRAL PROTEIN/REPLICATION INHIBITOR

Title :

Crystal structure of human norovirus RNA-dependent RNA-polymerase in complex with NAF2

Release Data :

2014-02-12

Compound :

mol_id	molecule	chains
1	RNA-dependent RNA-polymerase	A

Source :

mol_id	organism_scientific	expression_system
1	Norovirus (taxid:142786)	Escherichia coli (taxid:562)

Authors :

Milani, M., Tarantino, D., Mastrangelo, E., Croci, R.

Keywords :

RNA-dependent-RNA-polymerase, RdRp-inhibotir complex, VIRAL PROTEIN-REPLICATION INHIBITOR complex

Exp. method :

X-RAY DIFFRACTION ( 2.04 Å )

Citation :

Naphthalene-sulfonate inhibitors of human norovirus RNA-dependent RNA-polymerase.

Tarantino, D.,Pezzullo, M.,Mastrangelo, E. et al.
(2014) Antiviral Res. 102 : 23 - 28

Chain :

UniProt :

Q2N379 (Q2N379_9CALI)

Reaction:	EC:	Evidence:
Reaction:	Physiological Direction:	Evidence:
a ribonucleoside 5'-triphosphate + H2O = a ribonucleoside 5'- diphosphate + H(+) + phosphate	3.6.1.15	ARBA:ARBA00001491
	-	ARBA:ARBA00001491

PDB ID: 4LQ9