Brand  (β version)

PDB ID: 4L5J

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Ligands
Code Name Style Show Link
HSX 5-O-phosphono-alpha-D-ribofuranose PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 4L5J   PDBj   RCSB PDB   PDBe
Header : TRANSCRIPTION REGULATOR
Title : Crystal structures of the LsrR proteins complexed with phospho-AI-2 and its two different analogs reveal distinct mechanisms for ligand recognition
Release Data : 2013-11-06
Compound :
mol_id molecule chains
1 Transcriptional regulator LsrR A,B,C,D
Source :
mol_id organism_scientific expression_system
1 Escherichia coli  (taxid:83333) Escherichia coli  (taxid:562)
strain: K-12
gene: lsrR, ydeW, b1512, JW1505
expression_system_vector_type: plasmid
expression_system_plasmid: pGEX-4T-1
Authors : Ryu, K.S., Ha, J.H., Eo, Y.
Keywords : DNA transcriptional regulator, Phospho-AI-2 binding, DNA binding, TRANSCRIPTION REGULATOR, SorC/DeoR family, Helix-Turn-Helix domain
Exp. method : X-RAY DIFFRACTION ( 2.60 Å )
Citation :

Crystal Structures of the LsrR Proteins Complexed with Phospho-AI-2 and Two Signal-Interrupting Analogues Reveal Distinct Mechanisms for Ligand Recognition.

Ha, J.H.,Eo, Y.,Grishaev, A.  et al.
(2013)  J.Am.Chem.Soc.  135 : 15526 - 15535

PubMed: 24047255
DOI: 10.1021/ja407068v

Reaction

Chain : A, B, C, D
UniProt : P76141 (LSRR_ECOLI)
Reaction : -