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Ligands
Code Name Style Show Link
H6P (2e)-4-hydroxy-3-methylbut-2-en-1-yl trihydrogen diphosphate
Non-standard Residues
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Glycosylation
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Code : 4K55   PDBj   RCSB PDB   PDBe
Header : SIGNALING PROTEIN
Title : Structure of the extracellular domain of butyrophilin BTN3A1 in complex with (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate (HMBPP)
Release Data : 2013-07-24
Compound :
mol_id molecule chains
1 Butyrophilin subfamily 3 member A1 A
fragment: unp residues 28-143
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: BT3.2, BTF3, BTF4, BTF5, BTN3A1, BTN3A2, Butyrophilin subfamily 3 member A1
expression_system_vector_type: Plasmid
expression_system_plasmid: pET22b(+)-His6
Authors : Kumar, A., Mori, L., De Libero, G.
Keywords : immunoglobulin superfamily, SIGNALING PROTEIN
Exp. method : X-RAY DIFFRACTION ( 1.91 Å )
Citation :

Butyrophilin 3A1 binds phosphorylated antigens and stimulates human gamma delta T cells.

Vavassori, S.,Kumar, A.,Wan, G.S.  et al.
(2013)  Nat.Immunol.  14 : 908 - 916

PubMed: 23872678
DOI: 10.1038/ni.2665

Chain : A
UniProt : O00481 (BT3A1_HUMAN)
Reaction : -