PDB ID: 4JYI
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Structure summary
Code : | 4JYI PDBj RCSB PDB PDBe | ||||||||||||||||||||||||
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Header : | Transcription/Agonist | ||||||||||||||||||||||||
Title : | Crystal structure of RARbeta LBD in complex with selective partial agonist BMS641 [3-chloro-4-[(E)-2-(5,5-dimethyl-8-phenyl-5,6-dihydronaphthalen-2-yl)ethenyl]benzoic acid] | ||||||||||||||||||||||||
Release Data : | 2014-03-19 | ||||||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Nadendla, E.K., Teyssier, C., Germain, P., Delfosse, V., Bourguet, W. | ||||||||||||||||||||||||
Keywords : | Ligand binding domain, Nuclear hormone receptor, Transcription-Agonist complex | ||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.900 Å ) | ||||||||||||||||||||||||
Citation : |
An Unexpected Mode Of Binding Defines BMS948 as A Full Retinoic Acid Receptor beta (RAR beta , NR1B2) Selective Agonist.
Nadendla, E.,Teyssier, C.,Delfosse, V.
et al.
PubMed: 25933005 |
Reaction
Chain : | A, B |
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UniProt : | P10826 (RARB_HUMAN) |
Reaction : | - |
Chain : | F, G | ||||||||
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UniProt : | Q15788 (NCOA1_HUMAN) | ||||||||
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