Brand  (β version)

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
ACY Acetic acid
FMN Flavin mononucleotide
JS3 2-chloro-4-methyl-N-(naphthalen-2-yl)-1,3-thiazole-5-carboxamide
ORO Orotic acid
SO4 Sulfate ion
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show
Code : 4JS3   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 057
Release Data : 2014-03-26
Compound :
mol_id molecule chains synonym
1 Dihydroorotate dehydrogenase (quinone), mitochondrial A DHOdehase, Dihydroorotate oxidase
ec: 1.3.5.2
fragment: UNP residues 29-395
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: DHODH
Authors : Zhu, L., Li, H., Zhu, J., Ren, X.
Keywords : OXIDOREDUCTASE, FMN binding, mitochondrion inner membrane
Exp. method : X-RAY DIFFRACTION ( 2.000 Å )
Citation :

Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 057

Zhu, L.,Li, H.,Zhu, J.  et al.
TO BE PUBLISHED 

Chain : A
UniProt : Q02127 (PYRD_HUMAN)
Reaction: EC: Evidence:
Physiological Direction:
(S)-dihydroorotate + a quinone = a quinol + orotate 1.3.5.2 PubMed:8925840
-