Het-PDB Navi2 (PDB: 4JDD)

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Ligands
Code	Name		Style	Show	Link
FSC	Fusicoccin				PoSSuM

Non-standard Residues
Code	Name	Show
TPO	Phosphothreonine

Glycosylation
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Download interaction data: 4JDD

Code :

4JDD PDBj RCSB PDB PDBe

Header :

SIGNALING PROTEIN/Peptide

Title :

14-3-3 protein interaction with Estrogen Receptor Alpha provides a novel drug target interface

Release Data :

2013-05-15

Compound :

mol_id	molecule	chains	synonym
1	14-3-3 protein sigma	A	Epithelial cell marker protein 1, Stratifin
	fragment: UNP residues 1-231

mol_id	molecule	chains
2	Estrogen receptor Peptide	B
	fragment: UNP RESIDUES 585-595

Source :

mol_id	organism_scientific	organism_common	expression_system
1	Homo sapiens (taxid:9606)	Human	Escherichia coli (taxid:469008)
	gene: HME1, NM_006142, SFN expression_system_strain: ROSETTA (DE3) expression_system_vector_type: PLASMID expression_system_plasmid: PPROEX HTB

mol_id	organism_scientific	organism_common
2	Homo sapiens (taxid:9606)	Human
	synthetic: yes

Authors :

Bier, D., Ottmann, C.

Keywords :

14-3-3, ADAPTER PROTEIN, PROTEIN-PROTEIN INTERACTION, SIGNALING PROTEIN-Peptide complex

Exp. method :

X-RAY DIFFRACTION ( 2.1000 Å )

Citation :

Interaction of 14-3-3 proteins with the estrogen receptor alpha F domain provides a drug target interface.

De Vries-van Leeuwen, I.J.,da Costa Pereira, D.,Flach, K.D. et al.
(2013) Proc. Natl. Acad. Sci. U.S.A. 110 : 8894 - 8899

PDB ID: 4JDD