Brand  (β version)

PDB ID: 4JAO

Hetero Atom Contents

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
PLM Palmitic acid PoSSuM
JAO (2s)-2-methylheptadecan-1-ol PoSSuM
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show

Structure summary

Code : 4JAO   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Crystal Structure of Mycobacterium tuberculosis PKS11 Reveals Intermediates in the Synthesis of Methyl-branched Alkylpyrones
Release Data : 2013-04-24
Compound :
mol_id molecule chains synonym
1 Alpha-pyrone synthesis polyketide synthase-like Pks11 D,C,B,A Alpha-pyrone synthesis polyketide synthase type III Pks11, Chalcone synthase-like protein, CHS-like
ec: 2.3.1.-
Source :
mol_id organism_scientific expression_system
1 Mycobacterium tuberculosis  (taxid:1773) Mycobacterium smegmatis  (taxid:1772)
strain: H37RV
gene: pks11, Rv1665, MT1705
Authors : Gokulan, K., Sacchettini, J.C., Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
Keywords : lipid biosynthesis, Structural Genomics, Enzyme Function Initiative, ketosynthase enzyme, Alkylpyrone synthesis, TRANSFERASE, Mycobacterium Tuberculosis Structural Proteomics Project, XMTB
Exp. method : X-RAY DIFFRACTION ( 2.05 Å )
Citation :

Crystal structure of Mycobacterium tuberculosis polyketide synthase 11 (PKS11) reveals intermediates in the synthesis of methyl-branched alkylpyrones.

Gokulan, K.,O'Leary, S.E.,Russell, W.K.  et al.
(2013)  J.Biol.Chem.  288 : 16484 - 16494

PubMed: 23615910
DOI: 10.1074/jbc.M113.468892

Reaction

Chain : D, C, B, A
UniProt : O06587
Reaction : -