Het-PDB Navi2 (PDB: 4J8T)

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Ligands
Code	Name		Style	Show	Link
DOG	Digoxigenin				PoSSuM

Non-standard Residues
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Glycosylation
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Modification
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Download interaction data: 4J8T

Code :

4J8T PDBj RCSB PDB PDBe

Header :

DIGOXIGENIN BINDING PROTEIN

Title :

Engineered Digoxigenin binder DIG10.2

Release Data :

2013-06-26

Compound :

mol_id	molecule	chains
1	Engineered Digoxigenin binder protein DIG10.2	A,B,C,D
	mutation: L7V, S10A, F34Y, A37P, W41Y, H61Y, L62M, V64I, A90H, Q99A, D117L, W119F, H124V, A127P, G130L and V131E

Source :

mol_id	organism_scientific	expression_system
1	Pseudomonas aeruginosa (taxid:208964)	Escherichia coli (taxid:562)
	strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228 gene: PA3332 expression_system_strain: BL21(DE3)-RIL expression_system_vector_type: plasmid expression_system_plasmid: pET15

Authors :

Stoddard, B.L., Doyle, L.A.

Keywords :

engineered, computationally designed, Digoxigenin-binding, DIGOXIGENIN BINDING PROTEIN

Exp. method :

X-RAY DIFFRACTION ( 2.050 Å )

Citation :

Computational design of ligand-binding proteins with high affinity and selectivity.

Tinberg, C.E.,Khare, S.D.,Dou, J. et al.
(2013) Nature 501 : 212 - 216

PDB ID: 4J8T