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Ligands
Code Name Style Show Link
ZN Zinc ion
CVM Cymal-4
Non-standard Residues
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Glycosylation
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Code : 4IUV   PDBj   RCSB PDB   PDBe
Header : GENE REGULATION
Title : crystal structure of SHH1 SAWADEE domain in complex with H3K4me1K9me1 peptide
Release Data : 2013-05-01
Compound :
mol_id molecule chains synonym
1 SAWADEE HOMEODOMAIN HOMOLOG 1 B,A Uncharacterized protein
fragment: SHH1 SAWADEE domain (unp residues 125-258)
mol_id molecule chains
2 Histone H3.2, H3(1-15)K9me3 C
fragment: H3(1-15)K4me1K9me1 peptide (unp residues 2-16)
Source :
mol_id organism_scientific organism_common expression_system
1 Arabidopsis thaliana  (taxid:3702) Mouse-ear cress,thale-cress Escherichia coli  (taxid:469008)
gene: F9L1.16, At1g15215, AT1G15215
expression_system_strain: BL21(DE3)RIL
expression_system_vector_type: PLASMID
expression_system_plasmid: pET-SUMO
mol_id organism_scientific organism_common
2 Arabidopsis thaliana  (taxid:3702) Mouse-ear cress,thale-cress
synthetic: yes
other_details: H3(1-15)K4me1K9me1 peptide was synthesized
Authors : Du, J., Patel, D.J.
Keywords : tandem tudor, zinc finger, H3K9me2, mediate interaction, histone, methylation, GENE REGULATION
Exp. method : X-RAY DIFFRACTION ( 2.800 Å )
Citation :

Polymerase IV occupancy at RNA-directed DNA methylation sites requires SHH1.

Law, J.A.,Du, J.,Hale, C.J.  et al.
(2013)  Nature  498 : 385 - 389

PubMed: 23636332
DOI: 10.1038/nature12178

Chain : B, A
UniProt : Q9XI47 (SHH1_ARATH)
Reaction : -
Chain : C
UniProt : P59226 (H31_ARATH)
Reaction : -