Brand  (β version)

PDB ID: 4IQI

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Ligands
Code Name Style Show Link
CYT 6-aminopyrimidin-2(1h)-one PoSSuM
CL Chloride ion PoSSuM
Non-standard Residues
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MSE Selenomethionine
Glycosylation
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Structure summary

Code : 4IQI   PDBj   RCSB PDB   PDBe
Header : OXIDOREDUCTASE
Title : Crystal Structure of 7-cyano-7-deazaguanine Reductase, QueF from Vibrio cholerae O1 biovar El Tor complexed with cytosine
Release Data : 2013-01-23
Compound :
mol_id molecule chains synonym
1 NADPH-dependent 7-cyano-7-deazaguanine reductase A,B 7-cyano-7-carbaguanine reductase, NADPH-dependent nitrile oxidoreductase, PreQ(0) reductase
ec: 1.7.1.13
Source :
mol_id organism_scientific expression_system
1 Vibrio cholerae O1 biovar El Tor  (taxid:243277) Escherichia coli  (taxid:562)
strain: N16961
gene: queF, VCM66_0859
expression_system_strain: BL21 magic
expression_system_vector_type: plasmid
expression_system_plasmid: pMCSG7
Authors : Kim, Y., Zhou, M., Gu, M., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Keywords : Structural Genomics, NIAID, National Institute of Allergy and Infectious Diseases, Center for Structural Genomics of Infectious Diseases, CSGID, tunneling fold, Rossmann fold, OXIDOREDUCTASE
Exp. method : X-RAY DIFFRACTION ( 1.500 Å )
Citation :

Crystal Structure of 7-cyano-7-deazaguanine Reductase, QueF from Vibrio cholerae O1 biovar El Tor complexed with cytosine

Kim, Y.,Zhou, M.,Gu, M.  et al.
To be Published 

Reaction

Chain : A, B
UniProt : C3LTF1 (C3LTF1_VIBCM)
Reaction: EC: Evidence:
Physiological Direction:
7-aminomethyl-7-carbaguanine + 2 NADP(+) = 7-cyano-7- deazaguanine + 3 H(+) + 2 NADPH 1.7.1.13 HAMAP-Rule:MF_00817
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