Brand  (β version)

color scheme of protein:

hetatm:

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information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
F2Y 3,5-difluoro-L-tyrosine
Code : 4HJX
Header : LIGASE
Title : Crystal structure of F2YRS complexed with F2Y
Release Data : 2013-03-13
Compound :
mol_id molecule chains synonym
1 Tyrosine-tRNA ligase A,B Tyrosyl-tRNA synthetase, TyrRS
mutation: Y32R,L65Y,H70G,F108N,Q109C,D158N,L162S
Source :
mol_id organism_scientific expression_system
1 Methanococcus Jannaschii DSM 2661  (taxid:243232) Escherichia coli  (taxid:562)
strain: ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440
gene: tyrS, MJ0389
Authors : Wang, J., Tian, C., Gong, W., Li, F., Shi, P., Li, J., Ding, W.
Keywords : AMINOACYL-TRNA SYNTHETASE, LIGASE
Exp. method : X-RAY DIFFRACTION ( 2.910 Å )
Citation :

A genetically encoded 19F NMR probe for tyrosine phosphorylation.

Li, F.,Shi, P.,Li, J.  et al.
(2013)  Angew.Chem.Int.Ed.Engl.  52 : 3958 - 3962

PubMed: 23450644
DOI: 10.1002/anie.201300463

Chain : A, B
UniProt : Q57834 (SYY_METJA)
Reaction : ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + L-tyrosyl-tRNA(Tyr).