Brand  (β version)

PDB ID: 4GXS

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Ligands
Code Name Style Show Link
0YS (5r)-2-[(1s,2r)-2-amino-2-carboxy-1-hydroxyethyl]-5-{(2s)-2-carboxy-2-[(3,5-dichloro-4-hydroxybenzoyl)amino]ethyl}-L-proline PoSSuM
ZN Zinc ion PoSSuM
Non-standard Residues
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Structure summary

Code : 4GXS   PDBj   RCSB PDB   PDBe
Header : MEMBRANE PROTEIN
Title : Ligand binding domain of GluA2 (AMPA/glutamate receptor) bound to (-)-kaitocephalin
Release Data : 2012-10-17
Compound :
mol_id molecule chains synonym
1 Glutamate receptor 2 B,D GluR-2, AMPA-selective glutamate receptor 2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, GluA2
fragment: UNP Residues 652-794
Source :
mol_id organism_scientific organism_common expression_system
1 Rattus norvegicus  (taxid:10116) Brown rat,rat,rats Escherichia coli  (taxid:469008)
gene: Glur2, Gria2, Gria2; GluA2
expression_system_strain: Origami B (DE3)
expression_system_vector_type: PLASMID
expression_system_plasmid: pET-22b(+)
Authors : Ahmed, A.H., Oswald, R.E.
Keywords : glutamate receptor, GluA2, GluR2, AMPA receptor, neurotransmitter receptor, (-)-kaitocephalin, MEMBRANE PROTEIN
Exp. method : X-RAY DIFFRACTION ( 1.9634 Å )
Citation :

The structure of (-)-kaitocephalin bound to the ligand binding domain of the (S)-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)/glutamate receptor, GluA2.

Ahmed, A.H.,Hamada, M.,Shinada, T.  et al.
(2012)  J.Biol.Chem.  287 : 41007 - 41013

PubMed: 23076153
DOI: 10.1074/jbc.M112.416362

Reaction

Chain : B, D
UniProt : P19491 (GRIA2_RAT)
Reaction : -