Brand  (β version)

color scheme of protein:

hetatm:

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information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
0Y2 5'-{[(3s)-3-amino-3-carboxypropyl][2-(1-benzothiophen-3-yl)ethyl]amino}-5'-deoxyadenosine
Code : 4GOO
Header : TRANSFERASE
Title : Crystal Structure of E. coli DNA Adenine Methyltransferase in Complex with Benzothiophene Aza-SAM
Release Data : 2014-02-26
Compound :
mol_id molecule chains synonym
1 DNA adenine methylase D,E,F DNA adenine methyltransferase, Deoxyadenosyl-methyltransferase, M.EcoDam
ec: 2.1.1.72
Source :
mol_id organism_scientific expression_system
1 Escherichia coli  (taxid:83333) Escherichia coli  (taxid:469008)
strain: K-12
gene: b3387, dam, JW3350
expression_system_strain: BL21(DE3)
expression_system_vector_type: plasmid
expression_system_plasmid: pET24D
Authors : Harmer, J.E., Roach, P.L.
Keywords : Transferase, methylation
Exp. method : X-RAY DIFFRACTION ( 2.70 Å )
Citation :

Structural Basis of Selective N-6 adenine methyltransferase Inhibition by Transition State Mimic

Harmer, J.E.,McKelvie, J.C.,Hobley, G.  et al.
To be published 

Chain : D, E, F
UniProt : P0AEE8 (DMA_ECOLI)
Reaction : S-adenosyl-L-methionine + adenine in DNA = S- adenosyl-L-homocysteine + N-6-methyladenine in DNA.