PDB ID: 4GMB
Hetero Atom Contents
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Structure summary
Code : | 4GMB PDBj RCSB PDB PDBe | ||||||||||||||||||||||||
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Header : | TRANSCRIPTION/TRANSCRIPTION INHIBITOR | ||||||||||||||||||||||||
Title : | Crystal structure of human WD repeat domain 5 with compound MM-402 | ||||||||||||||||||||||||
Release Data : | 2014-02-19 | ||||||||||||||||||||||||
Compound : |
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Source : |
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Authors : | Karatas, H., Townsend, E.C., Chen, Y., Bernard, D., Cao, F., Liu, L., Lei, M., Dou, Y., Wang, S. | ||||||||||||||||||||||||
Keywords : | MLL1, histone methyltransferase, WD40, TRANSCRIPTION-TRANSCRIPTION INHIBITOR complex | ||||||||||||||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.781 Å ) | ||||||||||||||||||||||||
Citation : |
Discovery of a Highly Potent, Cell-Permeable Macrocyclic Peptidomimetic (MM-589) Targeting the WD Repeat Domain 5 Protein (WDR5)-Mixed Lineage Leukemia (MLL) Protein-Protein Interaction.
Karatas, H.,Li, Y.,Liu, L.
et al.
PubMed: 28603984 |
Reaction
Chain : | A |
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UniProt : | P61964 (WDR5_HUMAN) |
Reaction : | - |