PDB ID: 4GJ6
Hetero Atom Contents
The number of atoms exceeds 100,000. So, it can not be displayed here.
Select unit:
Select hetatm:
Select chain: Sequence
Data format:
Color scheme of protein:
Code | Name | Style | Show | Link | |
---|---|---|---|---|---|
0LS | N-{[(3s,4s)-4-benzylpyrrolidin-3-yl]methyl}-4-chloro-N-phenylaniline | PoSSuM | |||
SO4 | Sulfate ion | PoSSuM |
Code | Name | Show |
---|
Code | Name | Emphasize |
---|---|---|
NAG | 2-acetamido-2-deoxy-beta-D-glucopyranose |
Code | Name | Show |
---|
Download interaction data: 4GJ6
Structure summary
Code : | 4GJ6 PDBj RCSB PDB PDBe | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Header : | HYDROLASE/HYDROLASE INHIBITOR | ||||||||||||
Title : | Crystal structure of renin in complex with NVP-AYZ832 (compound 6a) | ||||||||||||
Release Data : | 2013-03-06 | ||||||||||||
Compound : |
|
||||||||||||
Source : |
|
||||||||||||
Authors : | Ostermann, N., Zink, F., Kroemer, M. | ||||||||||||
Keywords : | renin inhibitor, pharmacophore search, trans-3, 4-disubstituted pyrrolidine, HYDROLASE-HYDROLASE INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.58 Å ) | ||||||||||||
Citation : |
The Discovery of Novel Potent trans-3,4-Disubstituted Pyrrolidine Inhibitors of the Human Aspartic Protease Renin from in Silico Three-Dimensional (3D) Pharmacophore Searches.
Lorthiois, E.,Breitenstein, W.,Cumin, F.
et al.
PubMed: 23425156 |
Reaction
Chain : | A, B | ||||||||
---|---|---|---|---|---|---|---|---|---|
UniProt : | P00797 (RENI_HUMAN) | ||||||||
|