Brand  (β version)

PDB ID: 4GI7

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Ligands
Code Name Style Show Link
ADP Adenosine-5'-diphosphate PoSSuM
0JR (2r)-2,4-dihydroxy-3,3-dimethyl-N-{3-oxo-3-[(pyridin-3-ylmethyl)amino]propyl}butanamide PoSSuM
UNX Unknown atom or ion PoSSuM
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Structure summary

Code : 4GI7   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Crystal structure of Klebsiella pneumoniae pantothenate kinase in complex with a pantothenate analogue
Release Data : 2013-04-10
Compound :
mol_id molecule chains synonym
1 Pantothenate kinase A,C,B,D,E,F,G,H Pantothenic acid kinase
ec: 2.7.1.33
Source :
mol_id organism_scientific expression_system
1 Klebsiella pneumoniae  (taxid:507522) Escherichia coli  (taxid:469008)
strain: 342
gene: coaA, KPK_5321
expression_system_strain: BL21(DE3)
expression_system_vector_type: plasmid
expression_system_plasmid: pET28-MHL
Authors : Li, B., Tempel, W., Smil, D., Bolshan, Y., Hong, B.S., Park, H.W., Structural Genomics Consortium (SGC)
Keywords : protein-substrate complex, TRANSFERASE, Structural Genomics, Structural Genomics Consortium, SGC
Exp. method : X-RAY DIFFRACTION ( 1.9500 Å )
Citation :

Crystal structures of Klebsiella pneumoniae pantothenate kinase in complex with N-substituted pantothenamides.

Li, B.,Tempel, W.,Smil, D.  et al.
(2013)  Proteins  81 : 1466 - 1472

PubMed: 23553820
DOI: 10.1002/prot.24290

Reaction

Chain : A, C, B, D, E, F, G, H
UniProt : B5XYG3 (COAA_KLEP3)
Reaction: EC: Evidence:
Physiological Direction:
(R)-pantothenate + ATP = (R)-4'-phosphopantothenate + ADP + H(+) 2.7.1.33 HAMAP-Rule:MF_00215
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