PDB ID: 4GFG
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Structure summary
Code : | 4GFG PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE/TRANSFERASE INHIBITOR | ||||||||||||
Title : | Crystal structure of spleen tyrosine kinase complexed with r9021 | ||||||||||||
Release Data : | 2013-08-14 | ||||||||||||
Compound : |
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Source : |
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Authors : | Lukacs, C., Slade, M. | ||||||||||||
Keywords : | SYK, SPLEEN TYPROSINE KINASE, PYRIMIDINE-5-CARBOXAMIDE, ATP-BINDING, HOST-VIRUS INTERACTION, NUCLEOTIDE-BINDING, PHOSPHOPROTEIN, SH2 DOMAIN, TRANSFERASE-TRANSFERASE INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.35 Å ) | ||||||||||||
Citation : |
A specific SYK inhibitor blocks B Cell Receptor, Fc Receptor, and Toll-like Receptor 9 pathways for the treatment of inflammatory diseases.
Hsu, J.,Kim, Y.,Hu, D.-Q.
et al.
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Reaction
Chain : | A | ||||||||
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UniProt : | P43405 (KSYK_HUMAN) | ||||||||
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