Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain: Hide other chain(s)

Ligands
Code Name Link
CL Chloride ion
NI Nickel (II) ion
ZN Zinc ion
0WS 2-(1h-pyrazol-3-yl)pyridine-4-carboxylic acid
Code : 4GD4
Header : OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
Title : Crystal Structure of JMJD2A Complexed with Inhibitor
Release Data : 2012-08-15
Compound :
mol_id molecule chains synonym
1 Lysine-specific demethylase 4A A,B JmjC domain-containing histone demethylation protein 3A, Jumonji domain-containing protein 2A
ec: 1.14.11.-
fragment: catalytic domain
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: KDM4A, JHDM3A, JMJD2, JMJD2A, KIAA0677
Authors : King, O.N.F., Krojer, T., Arrowsmith, C.H., Edwards, A., Bountra, C., McDonough, M.A., Schofield, C.J., Structural Genomics Consortium (SGC)
Keywords : Structural Genomics, Structural Genomics Consortium, SGC, OXIDOREDUCTASE, JMJC DOMAIN, CHROMATIN REGULATOR, DIOXYGENASE, TRANSCRIPTION, DEMETHYLATION, IRON, 2-OXOGLUTARATE, ALPHA-KETOGLUTARATE, NUCLEUS, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex
Exp. method : X-RAY DIFFRACTION ( 2.33 Å )
Citation :

Crystal Structure of JMJD2A Complexed with Inhibitor

King, O.N.F.,Krojer, T.,Arrowsmith, C.H.  et al.
TO BE PUBLISHED 

Chain : A, B
UniProt : O75164 (KDM4A_HUMAN)
Reaction : -