PDB ID: 4G3G
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Structure summary
Code : | 4G3G PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE/TRANSFERASE INHIBITOR | ||||||||||||
Title : | Crystal structure of murine NF-kappaB inducing kinase (NIK) V408L bound to a 2-(aminothiazolyl)phenol (cmp3) | ||||||||||||
Release Data : | 2012-08-08 | ||||||||||||
Compound : |
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Source : |
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Authors : | Hymowitz, S. | ||||||||||||
Keywords : | non-RD kinase, protein serine/threonine kinase, NF-kappaB, MAP3K14, Structure-based drug design, transferase, TRANSFERASE-TRANSFERASE INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.50 Å ) | ||||||||||||
Citation : |
The crystal structure of the catalytic domain of the NF-kappaB inducing kinase reveals a narrow but flexible active site.
de Leon-Boenig, G.,Bowman, K.K.,Feng, J.A.
et al.
PubMed: 22921830 |
Reaction
Chain : | A | ||||||||||||
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UniProt : | Q9WUL6 (M3K14_MOUSE) | ||||||||||||
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