Brand  (β version)

PDB ID: 4G27

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Ligands
Code Name Style Show Link
CA Calcium ion PoSSuM
GOL Glycerol PoSSuM
PHU 1-phenylurea PoSSuM
SO4 Sulfate ion PoSSuM
Non-standard Residues
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Glycosylation
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Structure summary

Code : 4G27   PDBj   RCSB PDB   PDBe
Header : METAL TRANSPORT/CALCIUM BINDING PROTEIN
Title : Calcium-calmodulin complexed with the calmodulin binding domain from a small conductance potassium channel splice variant and phenylurea
Release Data : 2012-09-12
Compound :
mol_id molecule chains synonym
1 Small conductance calcium-activated potassium channel protein 2 B small conductance potassium channel splice variant, sk2a, SK2, SKCa 2, SKCa2, KCa2.2
fragment: calmodulin binding domain (UNP residues 396-487)
mol_id molecule chains synonym
2 Calmodulin R CaM
Source :
mol_id organism_scientific organism_common expression_system
1 Rattus norvegicus  (taxid:10116) Rat Escherichia coli  (taxid:562)
gene: Kcnn2
mol_id organism_scientific organism_common expression_system
2 Rattus norvegicus  (taxid:10116) Rat Escherichia coli  (taxid:562)
gene: Calm1, Calm, Cam, Cam1, Calm2, Cam2, Camb, Calm3, Cam3, Camc
Authors : Zhang, M., Pascal, J.M., Zhang, J.-F.
Keywords : protein-protein complex, EF Hand, metal binding protein, METAL TRANSPORT-CALCIUM BINDING PROTEIN complex
Exp. method : X-RAY DIFFRACTION ( 1.650 Å )
Citation :

Identification of the functional binding pocket for compounds targeting small-conductance Ca(2+)-activated potassium channels.

Zhang, M.,Pascal, J.M.,Schumann, M.  et al.
(2012)  Nat Commun  3 : 1021 - 1021

PubMed: 22929778
DOI: 10.1038/ncomms2017

Reaction

Chain : B
UniProt : P70604 (KCNN2_RAT)
Reaction : -
Chain : R
UniProt : P62161 (multiple entry names are found)
Reaction : -