PDB ID: 4G11
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Structure summary
Code : | 4G11 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | Transferase/Transferase Inhibitor | ||||||||||||
Title : | X-ray structure of PI3K-gamma bound to a 4-(morpholin-4-yl)- (6-oxo-1,6-dihydropyrimidin-2-yl)amide inhibitor | ||||||||||||
Release Data : | 2012-11-14 | ||||||||||||
Compound : |
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Source : |
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Authors : | Morales, R. | ||||||||||||
Keywords : | PHOSPHOINOSITIDE 3-KINASE GAMMA, SECONDARY MESSENGER GENERATION, Transferase-Transferase Inhibitor complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 3.40 Å ) | ||||||||||||
Citation : |
Preparation and optimization of new 4-(morpholin-4-yl)-(6-oxo-1,6-dihydropyrimidin-2-yl)amide derivatives as PI3K beta inhibitors
Certal, V.,Halley, F.,Virone-Oddos, A.
et al.
PubMed: 22981333 |
Reaction
Chain : | A | |||||||||||||||||||||||
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UniProt : | P48736 (PK3CG_HUMAN) | |||||||||||||||||||||||
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