PDB ID: 4FZ7
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Structure summary
Code : | 4FZ7 PDBj RCSB PDB PDBe | ||||||||||||
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Header : | TRANSFERASE/TRANSFERASE INHIBITOR | ||||||||||||
Title : | Crystal structure of spleen tyrosine kinase complexed with 6-((1R,2S)-2-Amino-cyclohexylamino)-4-(6-ethyl-pyridin-2-ylamino)-pyridazine-3-carboxylic acid amide | ||||||||||||
Release Data : | 2013-07-10 | ||||||||||||
Compound : |
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Source : |
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Authors : | Kuglstatter, A., Slade, M. | ||||||||||||
Keywords : | kinase inhibitor, TRANSFERASE-TRANSFERASE INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 1.75 Å ) | ||||||||||||
Citation : |
Using ovality to predict nonmutagenic, orally efficacious pyridazine amides as cell specific spleen tyrosine kinase inhibitors.
Lucas, M.C.,Bhagirath, N.,Chiao, E.
et al.
PubMed: 24520947 |
Reaction
Chain : | A | ||||||||
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UniProt : | P43405 (KSYK_HUMAN) | ||||||||
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