Brand  (β version)

PDB ID: 4FUG

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Ligands
Code Name Style Show Link
9UP Methyl (7-carbamimidoylnaphthalen-1-yl)carbamate PoSSuM
ACT Acetate ion PoSSuM
GOL Glycerol PoSSuM
SO4 Sulfate ion PoSSuM
Non-standard Residues
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Structure summary

Code : 4FUG   PDBj   RCSB PDB   PDBe
Header : HYDROLASE/HYDROLASE INHIBITOR
Title : Crystal Structure of the Urokinase
Release Data : 2012-08-22
Compound :
mol_id molecule chains synonym
1 Urokinase-type plasminogen activator A U-plasminogen activator, uPA, Urokinase-type plasminogen activator long chain A, Urokinase-type plasminogen activator short chain A, Urokinase-type plasminogen activator chain B
ec: 3.4.21.73
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: PLAU
Authors : Kang, Y.N., Stuckey, J.A., Nienaber, V., Giranda, V.
Keywords : HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR complex
Exp. method : X-RAY DIFFRACTION ( 1.8000 Å )
Citation :

Crystal Structure of the Urokinase

Kang, Y.N.,Stuckey, J.A.,Nienaber, V.  et al.
to be published 

Reaction

Chain : A
UniProt : P00749 (UROK_HUMAN)
Reaction: EC: Evidence:
Physiological Direction:
Specific cleavage of Arg-|-Val bond in plasminogen to form plasmin. 3.4.21.73 -
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