Brand  (β version)

PDB ID: 4FTK

Hetero Atom Contents

  The number of atoms exceeds 100,000.
  So, it can not be displayed here.

Select unit:

Select hetatm:   

close
information
centroid:
interaction residue:

Select chain:   Sequence  

Data format:   

Color scheme of protein:

Ligands
Code Name Style Show Link
H9K 3-(4'-hydroxybiphenyl-4-yl)-2,4-dihydroindeno[1,2-C]pyrazol-6-ol PoSSuM
IPA Isopropyl alcohol PoSSuM
SO4 Sulfate ion PoSSuM
Non-standard Residues
Code Name Show
Glycosylation
Code Name Emphasize
Modification
Code Name Show

Structure summary

Code : 4FTK   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE/TRANSFERASE inhibitor
Title : Crystal Structure of the CHK1
Release Data : 2012-08-22
Compound :
mol_id molecule chains synonym
1 Serine/threonine-protein kinase Chk1 A CHK1 checkpoint homolog, Cell cycle checkpoint kinase, Checkpoint kinase-1
ec: 2.7.11.1
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human HOMO SAPIENS  (taxid:9606)
strain: human
gene: CHEK1, CHK1
expression_system_common: Human
Authors : Kang, Y.N., Stuckey, J.A., Chang, P., Russell, A.J.
Keywords : TRANSFERASE, TRANSFERASE-TRANSFERASE inhibitor complex
Exp. method : X-RAY DIFFRACTION ( 2.3000 Å )
Citation :

Crystal Structure of the CHK1

Kang, Y.N.,Stuckey, J.A.,Chang, P.  et al.
To be Published 

Reaction

Chain : A
UniProt : O14757 (CHK1_HUMAN)
Reaction: EC: Evidence:
Physiological Direction:
L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+) 2.7.11.1 PubMed:10673501, PubMed:12660173, PubMed:14559997, PubMed:15659650, PubMed:15665856, PubMed:16511572, PubMed:16963448, PubMed:17296736, PubMed:17380128, PubMed:18317453, PubMed:18728393, PubMed:31316063, PubMed:9278511
-
L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+) 2.7.11.1 PubMed:10673501, PubMed:12660173, PubMed:14559997, PubMed:15659650, PubMed:15665856, PubMed:16511572, PubMed:16963448, PubMed:17296736, PubMed:17380128, PubMed:18317453, PubMed:18728393, PubMed:31316063, PubMed:9278511
-