Brand  (β version)

color scheme of protein:

hetatm:

chain:

Code Name Link
CSO S-hydroxycysteine
GOL Glycerol
H6K 1-(5-cyanopyrazin-2-yl)-3-(5-phenyl-1h-pyrazol-3-yl) urea
IPA Isopropyl alcohol
SO4 Sulfate ion
Code : 4FTC
Header : transferase/transferase inhibitor
Title : crystal structure of the chk1
Release Data : 2012-08-22
Compound :
mol_id 1
molecule serine/threonine-protein kinase chk1
chain A
synonym chk1 checkpoint homolog, cell cycle checkpoint kinase, checkpoint kinase-1
ec 2.7.11.1
engineered yes
Source :
mol_id 1
organism_scientific Homo sapiens
organism_common Human
organism_taxid 9606
strain human
gene chek1, chk1
expression_system Homo sapiens
expression_system_common Human
expression_system_taxid 9606
Authors : Y.N.Kang, J.A.Stuckey, P.Chang, A.J.Russell
Keywords : transferase, transferase-transferase inhibitor complex
Exp. method : X-ray diffraction ( 2.0 Å )
Chain : A
UniProt : O14757 (CHK1_HUMAN)
Reaction : ATP + a protein = ADP + a phosphoprotein.