Brand  (β version)

color scheme of protein:

hetatm:

x
information
centroid:
interaction residue:

chain:

Ligands
Code Name Link
0VY N'-sulfamoylpyrrolidine-1-carboximidamide
DMS Dimethyl sulfoxide
MBO Mercuribenzoic acid
ZN Zinc ion
Code : 4FRC
Header : LYASE/LYASE INHIBITOR
Title : Carbonic Anhydrase II in complex with N'-sulfamoylpyrrolidine-1-carboximidamide
Release Data : 2013-07-17
Compound :
mol_id molecule chains synonym
1 Carbonic anhydrase 2 A Carbonate dehydratase II, Carbonic anhydrase C, CAC, Carbonic anhydrase II, CA-II
ec: 4.2.1.1
Source :
mol_id organism_scientific organism_common expression_system
1 Homo sapiens  (taxid:9606) Human Escherichia coli  (taxid:562)
gene: CA2
expression_system_strain: BL21 CODON PLUS
expression_system_vector_type: PLASMID
expression_system_plasmid: PGEX-4T1
Authors : Di Pizio, A., Heine, A., Klebe, G.
Keywords : 10 STRANDED TWISTED BETA-SHEETS, LYASE, LYASE-LYASE INHIBITOR complex
Exp. method : X-RAY DIFFRACTION ( 0.98 Å )
Citation :

High resolution crystal structures of Carbonic Anhydrase II in complex with novel sulfamide binders

Di Pizio, A.,Schulze Wischeler, J.,Haake, M.  et al.
To be Published 

Chain : A
UniProt : P00918 (CAH2_HUMAN)
Reaction : H(2)CO(3) = CO(2) + H(2)O.