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Ligands
Code Name Style Show Link
CQA 4-[(7-chloroquinolin-4-yl)amino]-2-[(diethylamino)methyl]phenol
SAH S-adenosyl-L-homocysteine
PO4 Phosphate ion
Non-standard Residues
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Code : 4FGZ   PDBj   RCSB PDB   PDBe
Header : TRANSFERASE
Title : Crystal Structure of Phosphoethanolamine Methyltransferase from Plasmodium falciparum in Complex with Amodiaquine
Release Data : 2012-07-25
Compound :
mol_id molecule chains
1 Phosphoethanolamine N-methyltransferase A,B
ec: 2.1.1.103
Source :
mol_id organism_scientific expression_system
1 Plasmodium falciparum  (taxid:5833) Escherichia coli  (taxid:562)
gene: PMT
Authors : Lee, S.G., Alpert, T.D., Jez, J.M.
Keywords : SAM-dependent methyltransferase, SAM binding, methylation, TRANSFERASE
Exp. method : X-RAY DIFFRACTION ( 1.994 Å )
Citation :

Crystal structure of phosphoethanolamine methyltransferase from Plasmodium falciparum in complex with amodiaquine.

Lee, S.G.,Alpert, T.D.,Jez, J.M.
(2012)  Bioorg.Med.Chem.Lett.  22 : 4990 - 4993

PubMed: 22771008
DOI: 10.1016/j.bmcl.2012.06.032

Chain : A, B
UniProt : Q6T755
Reaction : -