PDB ID: 4FGH
Hetero Atom Contents
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Code | Name | Style | Show | Link | |
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0U6 | (2e)-3-{5-[(2,4-diamino-6-ethylpyrimidin-5-yl)methyl]-2,3-dimethoxyphenyl}-1-[(1s)-1-(2-methylprop-1-en-1-yl)phthalazin-2(1h)-yl]prop-2-en-1-one | PoSSuM | |||
GOL | Glycerol | PoSSuM | |||
NAP | Nadp nicotinamide-adenine-dinucleotide phosphate | PoSSuM |
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Download interaction data: 4FGH
Structure summary
Code : | 4FGH PDBj RCSB PDB PDBe | ||||||||||||
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Header : | OXIDOREDUCTASE/INHIBITOR | ||||||||||||
Title : | S. aureus dihydrofolate reductase co-crystallized with ethyl-DAP isobutenyl-dihydrophthalazine inhibitor | ||||||||||||
Release Data : | 2013-01-09 | ||||||||||||
Compound : |
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Authors : | Bourne, C.R., Barrow, W.W. | ||||||||||||
Keywords : | OXIDOREDUCTASE-INHIBITOR complex | ||||||||||||
Exp. method : | X-RAY DIFFRACTION ( 2.500 Å ) | ||||||||||||
Citation : |
Inhibition of Bacterial Dihydrofolate Reductase by 6-Alkyl-2,4-diaminopyrimidines.
Nammalwar, B.,Bourne, C.R.,Bunce, R.A.
et al.
PubMed: 22930550 |
Reaction
Chain : | A | ||||||||
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UniProt : | P0A017 (DYR_STAAU) | ||||||||
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